Abnormalities in heart rhythm continue to cause high rates of illness and death. Better
treatment could be provided by solving two main challenges: the early identification of
patients who are at risk, and the characterization of molecular pathways that culminate in
arrhythmias. By analysing mechanisms that increase susceptibility to arrhythmia in
individuals with genetic syndromes, it might be possible to improve current therapies and to
develop new ways to treat and prevent common arrhythmias.