Cerebrospinal fluid carnitine levels in patients with Parkinson's disease
FJ Jiménez-Jiménez, JC Rubio, JA Molina… - Journal of the …, 1997 - Elsevier
We assessed free carnitine (FC) and acyl-carnitine esters (AC) in both CSF and plasma from
29 patients with diagnostic criteria for PD, and from 29 healthy matched-controls. FC and AC
levels in both CSF and plasma did not differ significantly between PD patients and controls,
they were not influenced significantly by anti-parkinsonian drugs, and did not correlate with
age at onset, duration and severity of PD. These results suggest that CSF carnitine levels
are apparently unrelated with the risk for PD.© 1997 Elsevier Science BV All rights reserved.
29 patients with diagnostic criteria for PD, and from 29 healthy matched-controls. FC and AC
levels in both CSF and plasma did not differ significantly between PD patients and controls,
they were not influenced significantly by anti-parkinsonian drugs, and did not correlate with
age at onset, duration and severity of PD. These results suggest that CSF carnitine levels
are apparently unrelated with the risk for PD.© 1997 Elsevier Science BV All rights reserved.