Risk of lung cancer among white and black relatives of individuals with early-onset lung cancer
ML CotÚ, SLR Kardia, AS Wenzlaff, JC Ruckdeschel… - Jama, 2005 - jamanetwork.com
ContextEvidence exists that lung cancer aggregates in families and recent findings of a
chromosomal region linked to lung cancer susceptibility support a genetic component to risk.
Family studies of early-onset lung cancer patients offer a unique opportunity to evaluate
lifetime risk of lung cancer in relatives. ObjectiveTo measure lung cancer aggregation and
estimate lifetime risk among relatives of early-onset cases and population-based controls.
Design and SettingFamilial aggregation and cumulative risk estimates from interview data of …
chromosomal region linked to lung cancer susceptibility support a genetic component to risk.
Family studies of early-onset lung cancer patients offer a unique opportunity to evaluate
lifetime risk of lung cancer in relatives. ObjectiveTo measure lung cancer aggregation and
estimate lifetime risk among relatives of early-onset cases and population-based controls.
Design and SettingFamilial aggregation and cumulative risk estimates from interview data of …