The outer layer of the Candida albicans cell wall is enriched in highly glycosylated
mannoproteins that are the immediate point of contact with the host and strongly influence
the host-fungal interaction. N-Glycans are the major form of mannoprotein modification and
consist of a core structure, common to all eukaryotes, that is further elaborated in the Golgi to
form the highly branched outer chain that is characteristic of fungi. In yeasts, outer chain
branching is initiated by the action of the α1, 6-mannosyltransferase Och1p; therefore, we …