Molecular organization of the cell wall of Candida albicans

FM Klis, P Groot, K Hellingwerf - Medical mycology, 2001 - Taylor & Francis
Medical mycology, 2001Taylor & Francis
We have recently presented a molecular model of the cell wall of Saccharomyces
cerevisiae. Here we discuss the evidence that a similar model is also valid for Candida
albicans. We further discuss how cell-wall proteins are linked to the skeletal layer of the wall,
and their potential functions. We emphasize that the composition and structure of the cell
wall depends on growth conditions. Finally, cell-wall damage seems to activate a salvage
mechanism resulting in restructuring of the cell wall.
We have recently presented a molecular model of the cell wall of Saccharomyces cerevisiae. Here we discuss the evidence that a similar model is also valid for Candida albicans. We further discuss how cell-wall proteins are linked to the skeletal layer of the wall, and their potential functions. We emphasize that the composition and structure of the cell wall depends on growth conditions. Finally, cell-wall damage seems to activate a salvage mechanism resulting in restructuring of the cell wall.
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