Influence of Origin of Isolates, Especially Endocarditis Isolates, and Various Genes on Biofilm Formation by Enterococcus faecalis
JA Mohamed, W Huang, SR Nallapareddy… - Infection and …, 2004 - Am Soc Microbiol
JA Mohamed, W Huang, SR Nallapareddy, F Teng, BE Murray
Infection and immunity, 2004•Am Soc MicrobiolEndocarditis isolates of Enterococcus faecalis produced biofilm significantly more often than
nonendocarditis isolates, and 39% of 79 versus 6% of 84 isolates produced strong biofilm
(P< 0.0001). esp was not required, but its presence was associated with higher amounts of
biofilm (P< 0.001). Mutants disrupted in dltA, efaA, ace, lsa, and six two-component
regulatory systems were largely unaltered, while disruptions in epa, atn, gelE, and fsr
resulted in fewer attached bacteria, as determined using phase-contrast microscopy, and …
nonendocarditis isolates, and 39% of 79 versus 6% of 84 isolates produced strong biofilm
(P< 0.0001). esp was not required, but its presence was associated with higher amounts of
biofilm (P< 0.001). Mutants disrupted in dltA, efaA, ace, lsa, and six two-component
regulatory systems were largely unaltered, while disruptions in epa, atn, gelE, and fsr
resulted in fewer attached bacteria, as determined using phase-contrast microscopy, and …
Abstract
Endocarditis isolates of Enterococcus faecalis produced biofilm significantly more often than nonendocarditis isolates, and 39% of 79 versus 6% of 84 isolates produced strong biofilm (P < 0.0001). esp was not required, but its presence was associated with higher amounts of biofilm (P < 0.001). Mutants disrupted in dltA, efaA, ace, lsa, and six two-component regulatory systems were largely unaltered, while disruptions in epa, atn, gelE, and fsr resulted in fewer attached bacteria, as determined using phase-contrast microscopy, and less biofilm (P < 0.0001).
American Society for Microbiology