The physical parameters and molecular events associated with radiation-induced lung toxicity
Z Vujaskovic, LB Marks, MS Anscher - Seminars in radiation oncology, 2000 - Elsevier
Radiation therapy (RT) is frequently used to treat patients with tumors in and around the
thorax. Clinical radiation pneumonitis is a common side effect, occurring in 5% to 20% of
patients. Efforts to identify patients at risk for pneumonitis have focused on physical factors,
such as dose and volume. Recently, the underlying molecular biological mechanisms
behind RT-induced lung injury have come under study. Improved knowledge of the
molecular events associated with RT-induced lung injury may translated into a better ability …
thorax. Clinical radiation pneumonitis is a common side effect, occurring in 5% to 20% of
patients. Efforts to identify patients at risk for pneumonitis have focused on physical factors,
such as dose and volume. Recently, the underlying molecular biological mechanisms
behind RT-induced lung injury have come under study. Improved knowledge of the
molecular events associated with RT-induced lung injury may translated into a better ability …