Myelodysplastic transformation of polycythemia vera: case report and review of the literature
GJ Shamdas, CM Spier, AF List - American journal of …, 1991 - Wiley Online Library
GJ Shamdas, CM Spier, AF List
American journal of hematology, 1991•Wiley Online LibraryWe report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year
old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping
studies are described. In this report the clinical, cytogenetic and hematologic features of
myelodysplasia complicating polycythemia vera are reviewed. Results of
immunophenotyping and cytogenetic studies, and the preponderance of cases developing
after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is …
old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping
studies are described. In this report the clinical, cytogenetic and hematologic features of
myelodysplasia complicating polycythemia vera are reviewed. Results of
immunophenotyping and cytogenetic studies, and the preponderance of cases developing
after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is …
Abstract
We report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment‐related.
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