[HTML][HTML] Transcriptional regulation of the human biglycan gene
H Ungefroren, NB Krull - Journal of Biological Chemistry, 1996 - ASBMB
The small leucine-rich proteoglycan biglycan is involved in several physiological and
pathophysiological processes through the ability of its core protein to interact with other
extracellular matrix molecules and transforming growth factor-β (TGF-β). To learn more
about the regulation of biglycan core protein expression, we have cloned and sequenced
1218 base pairs from the 5′-flanking region of the human biglycan gene, demonstrated
functional promoter activity, and investigated the molecular mechanisms through which …
pathophysiological processes through the ability of its core protein to interact with other
extracellular matrix molecules and transforming growth factor-β (TGF-β). To learn more
about the regulation of biglycan core protein expression, we have cloned and sequenced
1218 base pairs from the 5′-flanking region of the human biglycan gene, demonstrated
functional promoter activity, and investigated the molecular mechanisms through which …
