[HTML][HTML] Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments
PJ Sheffield, CJ Oliver, BE Kremer, S Sheng… - Journal of Biological …, 2003 - ASBMB
Septins constitute a family of guanine nucleotide-binding proteins that were first discovered
in the yeastSaccharomyces cerevisiae but are also present in many other eukaryotes. In
yeast they congregate at the bud neck and are required for cell division. Their function in
metazoan cells is uncertain, but they have been implicated in exocytosis and cytokinesis.
Septins have been purified from cells as hetero-oligomeric filaments, but their mechanism of
assembly is unknown. Further studies have been limited by the difficulty in expressing …
in the yeastSaccharomyces cerevisiae but are also present in many other eukaryotes. In
yeast they congregate at the bud neck and are required for cell division. Their function in
metazoan cells is uncertain, but they have been implicated in exocytosis and cytokinesis.
Septins have been purified from cells as hetero-oligomeric filaments, but their mechanism of
assembly is unknown. Further studies have been limited by the difficulty in expressing …