Peripheral benzodiazepine receptors and mitochondrial function
P Casellas, S Galiegue, AS Basile - Neurochemistry international, 2002 - Elsevier
For over 20 years, numerous investigations have focused on elucidating the function of the
peripheral benzodiazepine receptor (PBR). This relatively small protein (18kDa) arouses
great interest because of its association with numerous biological functions, including the
regulation of cellular proliferation, immunomodulation, porphyrin transport and heme
biosynthesis, anion transport, regulation of steroidogenesis and apoptosis. Although the
receptor was first identified as a binding site for the benzodiazepine, diazepam, in peripheral …
peripheral benzodiazepine receptor (PBR). This relatively small protein (18kDa) arouses
great interest because of its association with numerous biological functions, including the
regulation of cellular proliferation, immunomodulation, porphyrin transport and heme
biosynthesis, anion transport, regulation of steroidogenesis and apoptosis. Although the
receptor was first identified as a binding site for the benzodiazepine, diazepam, in peripheral …