Methods to assess the development of cerebral damage need to be quantitative, reliable,
reproducible and safe. They must be acceptable to patients and to a healthy control group,
for repeated use and the acquisition and analytical methods must be stable over years.
Longitudinal studies are necessary to determine whether secondary cerebral damage
occurs as a consequence to the epilepsies. The principal aim of longitudinal studies is to
detect physical evidence of brain damage when it occurs. Patient groups will be …