Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene
M Hosoya, C Kimura, K Ogi, S Ohkubo… - … et Biophysica Acta (BBA …, 1992 - Elsevier
The human gene encoding pituitary adenylate cyclase activating polypeptide (PACAP) was
isolated and its nucleotide sequence was determined. By comparison with a human PACAP
cDNA, the exon/intron organization of PACAP gene was determined. The last exon encoded
the longer form of PACAP, PACAP38 and 3′-untranslated sequences, suggesting that the
shorter form of PACAP, PACAP27 is not generated by alternative splicing mechanisms. The
5′-flanking region of the PACAP gene contains several sequence motifs homologous to …
isolated and its nucleotide sequence was determined. By comparison with a human PACAP
cDNA, the exon/intron organization of PACAP gene was determined. The last exon encoded
the longer form of PACAP, PACAP38 and 3′-untranslated sequences, suggesting that the
shorter form of PACAP, PACAP27 is not generated by alternative splicing mechanisms. The
5′-flanking region of the PACAP gene contains several sequence motifs homologous to …