[HTML][HTML] Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells
C Yan, A Naltner, M Martin, M Naltner… - Journal of Biological …, 2002 - ASBMB
The function of the lung is dependent upon differentiation and proliferation of respiratory
epithelial cells and the synthesis/secretion of surfactant lipids and proteins into air space.
During the respiratory inflammatory response, cytokines produced by macrophages and
epithelial cells in the respiratory system have significant influence on surfactant protein
homeostasis. We report here that among family members of Janus family tyrosine kinase
(JAK) and signal transducers and activators of transcription (STAT), only JAK 1 and STAT3 …
epithelial cells and the synthesis/secretion of surfactant lipids and proteins into air space.
During the respiratory inflammatory response, cytokines produced by macrophages and
epithelial cells in the respiratory system have significant influence on surfactant protein
homeostasis. We report here that among family members of Janus family tyrosine kinase
(JAK) and signal transducers and activators of transcription (STAT), only JAK 1 and STAT3 …
