Galactocerebroside and not glucocerebroside or ceramide stimulate epidermal β-glucocerebrosidase activity
M Hara, Y Uchida, A Haratake, K Mimura… - Journal of …, 1998 - Elsevier
Glycosphingolipids including glucocerebroside (GluCer) and galactocerebroside (GalCer)
have been recognized as bioreguratory lipids by our group and others. In addition, our
recent study demonstrated that GalCer corrects dry skin conditions in humans. The
processing of stratum corneum lipids, which occurs when β-glucocerebrosidase (β-
GluCer'ase) changes GluCer to ceramide (Cer), is required to form the epidermal
permeability barrier. We herein investigated the effects of GluCer, GalCer and Cer on the …
have been recognized as bioreguratory lipids by our group and others. In addition, our
recent study demonstrated that GalCer corrects dry skin conditions in humans. The
processing of stratum corneum lipids, which occurs when β-glucocerebrosidase (β-
GluCer'ase) changes GluCer to ceramide (Cer), is required to form the epidermal
permeability barrier. We herein investigated the effects of GluCer, GalCer and Cer on the …