T cell immunity in lymphoid and non-lymphoid tissues
L Lefrançois, D Masopust - Current opinion in immunology, 2002 - Elsevier
L Lefrançois, D Masopust
Current opinion in immunology, 2002•ElsevierImmune responses to infection or effective vaccination generally result in the development of
memory lymphocytes capable of mounting a rapid response to secondary infection. Since
most infections initiate in non-lymphoid tissues, defense at these sites may be important for
protection. Recent results suggest that a substantial portion of the T cell response to
infection is focused in non-lymphoid tissues. Furthermore, anatomic localization appears to
define phenotypic and functional heterogeneity among antigen-specific memory T cell …
memory lymphocytes capable of mounting a rapid response to secondary infection. Since
most infections initiate in non-lymphoid tissues, defense at these sites may be important for
protection. Recent results suggest that a substantial portion of the T cell response to
infection is focused in non-lymphoid tissues. Furthermore, anatomic localization appears to
define phenotypic and functional heterogeneity among antigen-specific memory T cell …
Immune responses to infection or effective vaccination generally result in the development of memory lymphocytes capable of mounting a rapid response to secondary infection. Since most infections initiate in non-lymphoid tissues, defense at these sites may be important for protection. Recent results suggest that a substantial portion of the T cell response to infection is focused in non-lymphoid tissues. Furthermore, anatomic localization appears to define phenotypic and functional heterogeneity among antigen-specific memory T cell populations.
Elsevier