[HTML][HTML] Characterization of the heparan sulfate and chondroitin sulfate assembly sites in CD44
B Greenfield, WC Wang, H Marquardt… - Journal of Biological …, 1999 - ASBMB
Isoforms of CD44 are differentially modified by the glycosaminoglycans (GAGs) chondroitin
sulfate (CS), heparan sulfate (HS), and keratan sulfate. GAG assembly occurs at serines
followed by glycines (SG), but not all SG are utilized. Seven SG motifs are distributed in five
CD44 exons, and in this paper we identify the HS and CS assembly sites that are utilized in
CD44. Not all the CD44 SG sites are modified. The SGSG motif in CD44 exon V3 is the only
HS assembly site; this site is also modified with CS. HS and CS attachment at that site was …
sulfate (CS), heparan sulfate (HS), and keratan sulfate. GAG assembly occurs at serines
followed by glycines (SG), but not all SG are utilized. Seven SG motifs are distributed in five
CD44 exons, and in this paper we identify the HS and CS assembly sites that are utilized in
CD44. Not all the CD44 SG sites are modified. The SGSG motif in CD44 exon V3 is the only
HS assembly site; this site is also modified with CS. HS and CS attachment at that site was …