[HTML][HTML] Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents
HA Sampson, DG Ho - Journal of allergy and clinical immunology, 1997 - Elsevier
Background: The double-blind, placebo-controlled food challenge (DBPCFC) is the “gold
standard” for diagnosis of food hypersensitivity. Skin prick tests and RASTs are sensitive
indicators of food-specific IgE antibodies but poor predictors of clinical reactivity. Previous
studies suggested that high concentrations of food-specific IgE antibody were predictive of
food-induced clinical symptoms. Because the CAP System FEIA (Pharmacia Diagnostics,
Uppsala, Sweden) provides a quantitative assessment of allergen-specific IgE antibody, this …
standard” for diagnosis of food hypersensitivity. Skin prick tests and RASTs are sensitive
indicators of food-specific IgE antibodies but poor predictors of clinical reactivity. Previous
studies suggested that high concentrations of food-specific IgE antibody were predictive of
food-induced clinical symptoms. Because the CAP System FEIA (Pharmacia Diagnostics,
Uppsala, Sweden) provides a quantitative assessment of allergen-specific IgE antibody, this …