Human polymorphonuclear leukocyte phagocytosis in pregnancy: development of inhibition during gestation and recovery in the postpartum period
RH Persellin, LL Thoi - American journal of obstetrics and gynecology, 1979 - Elsevier
The phagocytosis of S. aureus by normal human PMN leukocytes was inhibited by
pregnancy serum. Control sera from normal adult nulliparous women, from men, and from
cord blood all functioned normally in support of phagocytosis. However, particle ingestion
was reduced significantly (p< 0.001) when leukocytes were in 15% pregnancy serum
obtained at term. To determine at what stage in pregnancy the inhibition of phagocytosis
could first be detected, sera were obtained from multiple pregnant donors and pooled …
pregnancy serum. Control sera from normal adult nulliparous women, from men, and from
cord blood all functioned normally in support of phagocytosis. However, particle ingestion
was reduced significantly (p< 0.001) when leukocytes were in 15% pregnancy serum
obtained at term. To determine at what stage in pregnancy the inhibition of phagocytosis
could first be detected, sera were obtained from multiple pregnant donors and pooled …