Gender differences in human sepsis

J Schröder, V Kahlke, KH Staubach, P Zabel… - Archives of …, 1998 - jamanetwork.com
Background In animal studies, gender differences were related to hormonal and
immunologic changes that were associated with an increased susceptibility to sepsis in
males. Objective In a prospective study, gender differences in patients with surgical sepsis
were evaluated in terms of survival, sex hormones, and proinflammatory as well as anti-
inflammatory mediators. Setting Surgical intensive care unit of a university hospital. Patients
Fifty-two patients (19 women and 33 men) with surgical sepsis. Measurements and Main …