Signal transduction through MAP kinase cascades
TS Lewis, PS Shapiro, NG Ahn - Advances in cancer research, 1998 - Elsevier
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of
combining biochemical and genetic approaches to molecular problems. The chapter
discusses the mammalian MAPK pathways—ERKl/2 and MKKl/2 pathways—and stress-
activated protein kinase pathways. The regulation of MAPK pathways by protein
phosphatases is discussed in the chapter describing in detail about dual specificity …
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of
combining biochemical and genetic approaches to molecular problems. The chapter
discusses the mammalian MAPK pathways—ERKl/2 and MKKl/2 pathways—and stress-
activated protein kinase pathways. The regulation of MAPK pathways by protein
phosphatases is discussed in the chapter describing in detail about dual specificity …
