[CITATION][C] [34] Separation of cytokeratin polypeptides by gel electrophoretic and chromatographic techniques and their identification by immunoblotting
T Achtstaetter, M Hatzfeld, RA Quinlan… - Methods in …, 1986 - Elsevier
The cytokeratins are a multigene family of proteins which are related to, but not identical
with, the" hard" a-keratins (" low sulfur proteins") of hairs and nails/-5 They form filamentous
structures which represent one of the five groups of intermediate filaments (IF) and are
characteristic differentiation markers for epithelial cells and epithelium-derived neoplasms. 6-
13 In human tissues 19 different cytokeratin polypeptides have been distinguished (Fig. I) 12
and similar numbers of different cytokeratins have been reported for other mammalian …
with, the" hard" a-keratins (" low sulfur proteins") of hairs and nails/-5 They form filamentous
structures which represent one of the five groups of intermediate filaments (IF) and are
characteristic differentiation markers for epithelial cells and epithelium-derived neoplasms. 6-
13 In human tissues 19 different cytokeratin polypeptides have been distinguished (Fig. I) 12
and similar numbers of different cytokeratins have been reported for other mammalian …