Gastrin is a target of the β-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis
J. Clin. Invest. Theodore J. Koh, et al. 106:533 doi:10.1172/JCI9476 [Go to this article.]

Figure 4
Effect of gastrin deficiency on polyp proliferation rates. (a) BrdU staining in 6-month old gastrin-deficient APC^min–/+ mice and (b) control APC^min–/+ mice. (c) Labeling indices were calculated by counting the number of immunopositive-staining cells as a percentage of the total number of cells in each polyp (^AP < 0.05) from both wild-type (filled bars) and gastrin-deficient mice (shaded bars).