Gastrin is a target of the β-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis
J. Clin. Invest. Theodore J. Koh, et al. 106:533 doi:10.1172/JCI9476 [Go to this article.]

Figure 2
Effect of overexpression of glycine-extended gastrin on APC^min–/+ mice. Total polyp number and the number of large polyps (>3 mm) in the small intestine from twenty 6-month-old APC^min–/+ mice that overexpress glycine-extended gastrin (MTI/G-Gly) (shaded bars) compared with twenty 6-month-old control APC^min–/+ mice (filled bars) in the same genetic background (^AP < 0.05).