Acute modulation of endothelial Akt/PKB activity alters nitric oxide–dependent vasomotor activity in vivo
J. Clin. Invest. Zhengyu Luo, et al. 106:493 doi:10.1172/JCI9419 [
Go to this article.]
Figure 2Constitutive activation of Akt promotes vasodilation that is reversed by infusion of
L-NAME. Vessel diameter was determined by quantitative angiography 3 days after endothelial infection. Data are expressed as the percentage change in vessel diameter relative to the base-line (untreated) diameter in the mock-infected (saline) group. Data are expressed as mean ± SEM (
n = 5).
