Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice
J. Clin. Invest. Gina C. Schatteman, et al. 106:571 doi:10.1172/JCI9087 [
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Figure 3CD34
+ cells are present in ischemic limb vasculature. Confocal images of 10-μm sections of muscle from an ischemic limb of two diabetic mice treated with CM-DiI–labeled CD34
+ cells. Sections from muscle collected 18 days after surgery were immunolabeled with FITC-conjugated anti–Tie-2 Ab. (
a and
b) The same section. (
c and
d) The same section. Confocal images of CM-DiI–labeled cells (white arrows) (
a,
c) that have formed vessels and are Tie-2 immunolabeled (black arrows) (
b,
d).