Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene
J. Clin. Invest. Jing Jin Gu, et al. 106:599 doi:10.1172/JCI8669 [Go to this article.]

Figure 6
Effect of loss of IMPDH II and HPRT activity on drug sensitivity. Wild-type (closed circles) or mutant (open circles) splenocytes were stimulated with either antibodies (a) or Con A (b) in the absence or presence of increasing concentrations of MPA. Data represent one of three highly similar experiments performed in triplicate (± SD) and are plotted as the percentage of proliferation in the absence of drug.