Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene
J. Clin. Invest. Jing Jin Gu, et al. 106:599 doi:10.1172/JCI8669 [Go to this article.]

Figure 1
Schema illustrating the pathways of de novo and salvage purine nucleotide biosynthesis. Solid lines represent the de novo purine biosynthetic pathway, and dashed lines indicate salvage pathways. APRT, adenine phosphoribosyltransferase; AMP-DA, AMP-deaminase.