Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia
J. Clin. Invest. Serena Y. Tan, et al. 117:3742 doi:10.1172/JCI33284 [Go to this article.]

Figure 6
Necropsies showing outflow tract defects in Dnahc5^del593 mutants. (A) D-malposition of great vessels is shown with levocardia with anterior and rightward Ao relative to the PA. EFIC analysis showed that this heart was D-looped with D-TGA. (B) Dextrocardia with anterior and leftward aorta indicating L-malposition of great vessels. EFIC showed this was a D-looped heart with L-TGA. (C) Mesocardia with parallel great vessels and right-sided aorta, i.e., D-malposition. EFIC showed that this heart was D-looped with D-TGA. (D) Dextrocardia with parallel great vessels and left-sided aorta, i.e., L-malposition. EFIC showed that this heart was D-looped with DORV. Scale bar: 1 mm.