Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia
J. Clin. Invest. Baozhi Yuan, et al. 118:722 doi:10.1172/JCI32702 [
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Figure 8Real-time PCR results demonstrated the phosphatonin mRNA expression in normal,
hyp-,
OC-Cre-PhexΔflox/y, and
Cre-PhexΔflox/y mouse bone samples.
Production of FGF-23, MEPE, and sFRP-4 was increased in
hyp- and
Cre-PhexΔflox/y mice. However, only FGF-23 production was increased in
OC-Cre-PhexΔflox/y mice. *
P < 0.05, **
P < 0.01 compared with corresponding normal mice.
