Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia
J. Clin. Invest. Baozhi Yuan, et al. 118:722 doi:10.1172/JCI32702 [
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Figure 2Pi transport across renal brush border membrane and Npt2 protein content in the kidney. (
A) Both knockout mice exhibited decreased renal Pi transport in renal brush border membranes, similar to that in
hyp-mice, when compared with the normal controls. (
B) Western blotting showed comparable decreases in the renal tubular Npt2 cotransporter in both knockout and
hyp-mice when compared with the normal controls. *
P < 0.05, **
P < 0.01 compared with normal mice.