Factor I is required for the development of membranoproliferative glomerulonephritis in factor H–deficient mice
J. Clin. Invest. Kirsten L. Rose, et al. 118:608 doi:10.1172/JCI32525 [Go to this article.]

Figure 3
Light microscopic appearances of mesangial hyalinosis in 8-month-old Cfi^–/– mice. PAS-stained glomerular sections from 8-month-old wild-type (A) and Cfi^–/– mice (B and C). The glomerulus from the wild-type mouse had normal appearances. In contrast, areas of mesangial expansion with a nodular hyaline appearance were evident in the Cfi^–/– mice (arrows). Original magnification, ×40 (B); ×100(A and C).