Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice
J. Clin. Invest. Jennifer Kelly, et al. 117:3421 doi:10.1172/JCI32430 [Go to this article.]

Figure 2
Assessment of CNV inhibition following intraocular injection of macrophages (1 × 10⁵ cells/eye). Old mice were injected with PBS (sham) or macrophages from either old or young mice on the day of laser, and CNV was measured at day 7 following laser injury. Macrophages isolated from young mice demonstrated significant inhibition of CNV following intraocular injection in to old eyes, while macrophages isolated from old mice fail to inhibit CNV. *P < 0.02, young vs. old.