Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent
J. Clin. Invest. Benyue Zhang, et al. 117:3029 doi:10.1172/JCI32426 [Go to this article.]

Figure 2
Loss of CD8⁺ T cells in anti-CD137–injected virus-infected mice. C57BL/6 mice were infected by i.p. injection of 2 × 10⁵ PFU LCMV Armstrong. The following day, mice were injected i.p. with 200 μg of either anti-CD137 or rat IgG. Mice were euthanized on day 8 P.I. and CD8⁺ T cells enumerated by FACS analysis in (A) spleen, (B) pooled left and right inguinal LNs, and (C) lung.