Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence
J. Clin. Invest. Attila Gácser, et al. 117:3049 doi:10.1172/JCI32294 [
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Figure 7Endothelial damage assay of
C. parapsilosis WT, heterozygous mutant
CpLIP1-2/Δcplip1-2, homozygous mutant
Δcplip1-2/Δcplip1-2, and reconstituted
Δcplip1-2/CpLIP2 mutant.
C. albicans SC5314 cells were used as a positive control. HUVEC lysis was measured after 8 hours by LDH assay. Error bars indicate SD. The assay was repeated 3 times.
