Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence
J. Clin. Invest. Attila Gácser, et al. 117:3049 doi:10.1172/JCI32294 [
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Figure 3Growth curves of
C. parapsilosis WT and lipase mutants in YPD, YNB, YNB–olive oil, and in YNB-intralipid media.
Growth curves of the WT strain and heterozygous
CpLIP1-2/Δcplip1-2, homozygous
Δcplip1-2/Δcplip1-2, and reconstituted
Δcplip1-2/CpLIP2 mutants in YPD (
A), YNB (
B), and YNB–olive oil (
C) media. (
D) CFU in YNB-intralipid solution. Error bars indicate SD. The experiment was repeated, and similar results were found.
