Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages
J. Clin. Invest. Lisa C. Zaba, et al. 117:2517
doi:10.1172/JCI32282 [Go to this article.]

Figure 1
FXIIIA+ and CD11c+ cells are unique dermal populations. (A) Immunohistochemistry on normal human skin using FXIIIA (left panel) and CD11c (right panel) antibodies (n = 15). FXIIIA+ cells were spread throughout the dermis, while CD11c+ cells were mainly localized to the superficial dermis. (B) There were similar numbers of CD11c+ and FXIIIA+ cells per mm in normal dermis. Error bars indicate SEM. (C) FXIIIA and CD11c identified 2 discrete populations. White lines denote dermo-epidermal junction. Scale bars: 100 μm.