Type I IFN innate immune response to adenovirus-mediated IFN-γ gene transfer contributes to the regression of cutaneous lymphomas
J. Clin. Invest. Mirjana Urosevic, et al. 117:2834 doi:10.1172/JCI32077 [
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Figure 5Expression of MX1 (MXA), MX2 (MXB), UBE2L6, CXCL11, and IFITM1 genes that have value in predicting OR. (
A–
E) The left panel shows a box plot that represents the summarized expression of the respective gene in baseline and posttreatment 3 samples (
y axis) normalized to CD4 and are grouped with respect to OR (
x axis). Each box shows the median (thick black line), quartile range (the box itself), and minimum/maximum (whiskers). Outliers (values between 1.5 and 3 box lengths from either end of the box) are denoted by white circles. Extreme values (values that are more than 3 box lengths from either end of the box) are marked by asterisks. The right panel represents the ROC curve generated for the expression of the respective gene at posttreatment 3. For each gene, the
P value of area under the curve is shown in parentheses.