Type I IFN innate immune response to adenovirus-mediated IFN-γ gene transfer contributes to the regression of cutaneous lymphomas
J. Clin. Invest. Mirjana Urosevic, et al. 117:2834 doi:10.1172/JCI32077 [
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Figure 1Functional annotation of genes upregulated after treatment with Ad-IFN-γ using the GO mining tool (NetAffx). The GO mining tool maps 213 queried genes and groups them hierarchically according to the GO biological processes in which they participate (GO term), represented by colored rectangles (nodes). The node color represents the value of the c
2 test used by the GO mining tool to measure the grouping probability of the queried genes (highest values shown in red and lower values in blue). Node text contains the GO term ID, the GO term title, and the number of queried genes belonging to that GO term shown in parentheses; the value of the c
2 test for the respective GO term is shown below. Genes of interest are additionally listed in detail. Genes are identified by their gene symbols and fold change in expression (posttreatment 3 versus baseline), shown in parentheses.
