A Foxo/Notch pathway controls myogenic differentiation and fiber type specification
J. Clin. Invest. Tadahiro Kitamura, et al. 117:2477 doi:10.1172/JCI32054 [
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Figure 3Foxo1 coimmunoprecipitates with Csl. (
A) Coimmunoprecipitation of endogenous Foxo1 and Csl in C2C12 cells cocultured with LacZ-expressing (denoted by the minus sign) or Jagged1-expressing HEK293 cells (denoted by the plus sign). (
B and
C) Coimmunoprecipitation experiments in C2C12 cells cotransfected with FLAG-Csl and HA-Foxo1. (
D and
E) Coimmunoprecipitation experiments in C2C12 cells cotransfected with FLAG-Csl and the truncated mutant Myc- or HA-tagged Δ256 Foxo1. TCL, total cellular lysate.
