Molecular pathogenesis of emphysema
J. Clin. Invest. Laimute Taraseviciene-Stewart, et al. 118:394 doi:10.1172/JCI31811 [
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Figure 2Human emphysema. (
A) Chest CT scan of a 56-year-old man with COPD demonstrating a profound loss of the lung parenchyma and paucity of lung vessels. (
B) Whole-lung section demonstrating ubiquitous “holes,” i.e., emphysema. (
C) Histology of end-stage emphysematous lung. H&E staining; magnification, ×40. The loss of alveolar septal cells is not accompanied (in this specimen) by significant inflammatory cell accumulation.