Molecular pathogenesis of emphysema
J. Clin. Invest. Laimute Taraseviciene-Stewart, et al. 118:394
doi:10.1172/JCI31811 [Go to this article.]

Figure 2
Human emphysema. (A) Chest CT scan of a 56-year-old man with COPD demonstrating a profound loss of the lung parenchyma and paucity of lung vessels. (B) Whole-lung section demonstrating ubiquitous “holes,” i.e., emphysema. (C) Histology of end-stage emphysematous lung. H&E staining; magnification, ×40. The loss of alveolar septal cells is not accompanied (in this specimen) by significant inflammatory cell accumulation.