Discovery of the Philadelphia chromosome: a personal perspective
J. Clin. Invest. Peter C. Nowell, et al. 117:2033 doi:10.1172/JCI31771 [Go to this article.]

Figure 1
Karyotype of an individual with CML. A chromosomal preparation of cells at the metaphase stage of mitosis was stained with Giemsa, which binds A-T base pairs. The Philadelphia chromosome (the minute, defective chromosome 22 indicated by the right arrow) results from reciprocal translocation between chromosomes 9 and 22. Left arrow indicates portion of chromosome 22 translocated to chromosome 9. Figure reproduced with permission from eMedicine.com (26).