Celiac disease: pathogenesis of a model immunogenetic disease
J. Clin. Invest. Martin F. Kagnoff, et al. 117:41 doi:10.1172/JCI30253 [Go to this article.]

Figure 1
Small-intestinal mucosal biopsy. (A and B) Small-intestinal mucosal biopsy viewed through a dissecting microscope. The normal biopsy (A) shows numerous surface villi, whereas a biopsy from an individual with CD and total villous atrophy shows, in place of the villi, numerous surface openings to underlying crypts and surface ridges (B). (C) H&E-stained section of a normal small-intestinal mucosal biopsy. Original magnification, ×400. (D) H&E-stained section of a small-intestinal mucosal biopsy from an individual with CD and total villous atrophy. Original magnification, ×400. All panels reprinted with from Gastroenterology (1) with permission from the American Gastroenterological Association.