Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia
J. Clin. Invest. Christopher Jones, et al. 117:165 doi:10.1172/JCI29415 [Go to this article.]

Figure 6
Internalization of IgG-C7 and IgG-C7:protein A complexes in primary hepatocytes. Primary hepatocytes were isolated from Arh^+/+Ldlr^h/h, Arh^–/–Ldlr^h/h, and Arh^+/+Ldlr^–/– mice and incubated for 1 hour at 4°C with either (A) IgG-C7 or (B) IgG-C7 complexed with protein A. Cells were then warmed to 37°C for 2 hours. IgG-C7 was detected by indirect immunofluorescence confocal microscopy. Original magnification, ×130.