Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression
J. Clin. Invest. Patrick Collombat, et al. 117:961 doi:10.1172/JCI29115 [Go to this article.]

Figure 1
Generation of animals conditionally misexpressing the Arx gene. Schematic depicting the targeting vector before (top) and after (bottom) recombination of the 2 LoxP sites induced by the phage P1 Cre recombinase. β-Galactos., β-galactosidase. Inset: Visual examination of representative Cre-negative E10 embryo and adult pancreas under fluorescent light. Original magnification, ×40.