Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
J. Clin. Invest. Jun Zhang, et al. 116:3042 doi:10.1172/JCI28746 [Go to this article.]

Figure 7
COX-2 and iNOS immunostaining of tissue sections obtained from wild-type and Cyld^–/– mice 7 days after the first, second, and third cycles of DSS treatment. Numerous COX-2–positive cells were observed in the epithelium, and iNOS-positive cells were observed within broadly based inflammatory infiltrating cells, of the adenomatous tissue of Cyld^–/– mice. Arrowheads indicate positively stained cells. Magnification, ×50.