Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
J. Clin. Invest. Jun Zhang, et al. 116:3042 doi:10.1172/JCI28746 [
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Figure 5Comparison of cellular JNK levels in
Cyld–/– and wild-type cells.
(
A) Lysates prepared from peritoneal macrophages stimulated with LPS or TNF-α were Western blotted with phosphospecific (P-) antibodies recognizing activated JNKs. (
B) Lysates prepared from T cells stimulated with anti-CD3 were Western blotted with phosphospecific antibodies recognizing activated JNKs. SAPK, stress-activated protein kinase.