Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
J. Clin. Invest. Foteini Mourkioti, et al. 116:2945 doi:10.1172/JCI28721 [
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Figure 2IKK2 muscle depletion increases number of intermediate fibers. (
A and
B) Increased number of intermediate fibers in
Ikk2mko soleus with similar number of slow fibers. (
C) Mean percentage increase in
Ikk2mko soleus total CSA. (
D–
F) The number of intermediate fibers in the
Ikk2mko EDL was modestly but not significantly increased while the number of other fiber types remained unaltered. (
G) Mean percentage of total CSA of the EDL was similar between control and
Ikk2mko animals. **Mean values differ significantly from those of control (
P < 0.002).