Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin
J. Clin. Invest. Liat Linde, et al. 117:683 doi:10.1172/JCI28523 [
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Figure 4Relative levels of physiologic NMD substrates in RNA samples derived from CF patients. The level of each analyzed transcript —
RPL3 (
A),
SC35 1.7 kb (
B),
SC35 1.6 kb (
C),
ASNS (
D), and
CARS (
E) — was measured by real-time PCR and normalized to the level of
GAPDH. The relative levels are shown as mean ± SEM.
