Cardiac autophagy is a maladaptive response to hemodynamic stress
J. Clin. Invest. Hongxin Zhu, et al. 117:1782 doi:10.1172/JCI27523 [
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Figure 3Time course of autophagic activity in sTAB ventricle and changes in Beclin 1 protein levels. (
A) Autophagic activity induced in the basal septum in response to sTAB was quantified by counting GFP-LC3 dots per microscopic field (14,479 μm
2). Representative immunoblot for Beclin 1 showed an increase in Beclin 1 abundance following sTAB (
B) but not in response to short-term nutrient deprivation (
C). *
P < 0.05 versus sham. Ctl, control.